Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway

Neuropilin 1 (NRP1), a non-tyrosine kinase receptor for vascular endothelial growth factor and class 3 Semaphorins, is highly expressed in many human tumour cell lines, but its function is poorly understood. Here, we describe the expression of a new chondroitin sulphate-modified NRP1 (NRP1-CS) in hu...

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Detalhes bibliográficos
Main Authors: Frankel, Paul, Pellet-Many, Caroline, Lehtolainen, Pauliina, D'Abaco, Giovanna M, Tickner, Michelle L, Cheng, Lili, Zachary, Ian C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572126/
https://ncbi.nlm.nih.gov/pubmed/18704117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.151
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