Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA

In budding yeast the cullin Rtt101 promotes replication fork progression through natural pause sites and areas of DNA damage, but its relevant subunits and molecular mechanism remain poorly understood. Here, we show that in budding yeast Mms1 and Mms22 are functional subunits of an Rtt101-based ubiq...

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Detalhes bibliográficos
Main Authors: Zaidi, Iram Waris, Rabut, Gwénaël, Poveda, Ana, Scheel, Hartmut, Malmström, Johan, Ulrich, Helle, Hofmann, Kay, Pasero, Philippe, Peter, Matthias, Luke, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572122/
https://ncbi.nlm.nih.gov/pubmed/18704118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.155
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