Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA

In budding yeast the cullin Rtt101 promotes replication fork progression through natural pause sites and areas of DNA damage, but its relevant subunits and molecular mechanism remain poorly understood. Here, we show that in budding yeast Mms1 and Mms22 are functional subunits of an Rtt101-based ubiq...

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Autori principali: Zaidi, Iram Waris, Rabut, Gwénaël, Poveda, Ana, Scheel, Hartmut, Malmström, Johan, Ulrich, Helle, Hofmann, Kay, Pasero, Philippe, Peter, Matthias, Luke, Brian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
Soggetti:
Scientific Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572122/
https://ncbi.nlm.nih.gov/pubmed/18704118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.155
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