Lack of association of colonic epithelium telomere length and oxidative DNA damage in Type 2 diabetes under good metabolic control

BACKGROUND: Telomeres are DNA repeat sequences necessary for DNA replication which shorten at cell division at a rate directly related to levels of oxidative stress. Critical telomere shortening predisposes to cell senescence and to epithelial malignancies. Type 2 diabetes is characterised by increa...

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Main Authors: Kejariwal, Deepak, Stepien, Karolina M, Smith, Tracy, Kennedy, Hugh, Hughes, David A, Sampson, Mike J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572056/
https://ncbi.nlm.nih.gov/pubmed/18847490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6823-8-12
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