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Biochemical enhancement of transdermal delivery with magainin peptide: Modification of electrostatic interactions by changing pH

Magainin is a naturally occurring, pore-forming peptide that has recently been shown to increase skin permeability. This study tested the hypothesis that electrostatic forces between magainin peptides and drugs mediate drug transport across the skin. Electrostatic interaction between positively char...

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Detalhes bibliográficos
Main Authors: Kim, Yeu-Chun, Late, Sameer, Banga, Ajay K., Ludovice, Peter J., Prausnitz, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572033/
https://ncbi.nlm.nih.gov/pubmed/18601987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2008.05.042
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