Identification of Serotype in Culture Negative Pneumococcal Meningitis Using Sequential Multiplex PCR: Implication for Surveillance and Vaccine Design

BACKGROUND: PCR-based serotyping of Streptococcus pneumoniae has been proposed as a simpler approach than conventional methods, but has not been applied to strains in Asia where serotypes are diverse and different from other part of the world. Furthermore, PCR has not been used to determine serotype...

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Main Authors:	Saha, Samir K., Darmstadt, Gary L., Baqui, Abdullah H., Hossain, Belal, Islam, Maksuda, Foster, Dona, Al-Emran, Hassan, Naheed, Aliya, Arifeen, Shams El, Luby, Stephen P., Santosham, Mathuram, Crook, Derrick
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2008
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2571985/ https://ncbi.nlm.nih.gov/pubmed/18974887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003576
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Identification of Serotype in Culture Negative Pneumococcal Meningitis Using Sequential Multiplex PCR: Implication for Surveillance and Vaccine Design

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