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CD40L(+) CD4(+) memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming

There is growing evidence that the maturation state of dendritic cells (DCs) is a critical parameter determining the balance between tolerance and immunity. We report that mouse CD4(+) effector memory T (T(EM)) cells, but not naive or central memory T cells, constitutively expressed CD40L at levels...

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Detalhes bibliográficos
Main Authors: Martín-Fontecha, Alfonso, Baumjohann, Dirk, Guarda, Greta, Reboldi, Andrea, Hons, Miroslav, Lanzavecchia, Antonio, Sallusto, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571931/
https://ncbi.nlm.nih.gov/pubmed/18838544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081212
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