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In vivo administration of recombinant growth hormone or gamma interferon activities macrophages: enhanced resistance to experimental Salmonella typhimurium infection is correlated with generation of reactive oxygen intermediates.

Purified and recombinant forms of growth hormone (GH) as well as of recombinant rat gamma interferon (IFN-gamma) enhance the survival of rats deprived of endogenous pituitary GH secretion by hypophysectomy (HX rats) and infected with virulent Salmonella typhimurium. Macrophages obtained from rats wi...

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Bibliographic Details
Main Authors: Edwards, C K, Ghiasuddin, S M, Yunger, L M, Lorence, R M, Arkins, S, Dantzer, R, Kelley, K W
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC257190/
https://ncbi.nlm.nih.gov/pubmed/1316877
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