Aldose Reductase Genotypes and Cardiorenal Complications: An 8-year prospective analysis of 1,074 type 2 diabetic patients

OBJECTIVE—We report the independent risk association of type 2 diabetic nephropathy with the z−2 allele of the 5′-(CA)(n) microsatellite and C-106T promoter polymorphisms of the aldose reductase gene (ALR2) using a case-control design. In this expanded cohort, we examined their predictive roles on n...

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Bibliographic Details
Main Authors: So, Wing-Yee, Wang, Ying, Ng, Maggie C.Y., Yang, Xilin, Ma, Ronald C.W., Lam, Vincent, Kong, Alice P.S., Tong, Peter C.Y., Chan, Juliana C.N.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2008
Subjects:
Epidemiology/Health Services Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571065/
https://ncbi.nlm.nih.gov/pubmed/18716049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc08-0712
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