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Effect of host cell lipid metabolism on alphavirus replication, virion morphogenesis, and infectivity
The alphavirus Sindbis virus (SINV) causes encephalomyelitis in mice. Lipid-containing membranes, particularly cholesterol and sphingomyelin (SM), play important roles in virus entry, RNA replication, glycoprotein transport, and budding. Levels of SM are regulated by sphingomyelinases (SMases). Acid...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2571027/ https://ncbi.nlm.nih.gov/pubmed/18845681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808720105 |
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