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Dyggve–Melchior–Clausen syndrome: Chondrodysplasia resulting from defects in intracellular vesicle traffic

Dyggve–Melchior–Clausen syndrome and Smith-McCort dysplasia are recessive spondyloepimetaphyseal dysplasias caused by loss-of-function mutations in dymeclin (Dym), a gene with previously unknown function. Here we report that Dym-deficient mice display defects in endochondral bone formation similar t...

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Detalhes bibliográficos
Main Authors: Osipovich, Anna B., Jennings, Jennifer L., Lin, Qing, Link, Andrew J., Ruley, H. Earl
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571016/
https://ncbi.nlm.nih.gov/pubmed/18852472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804259105
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