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Delivery and expression of a heterologous antigen on the surface of streptococci.

We have developed a system in which a foreign antigen replaces nearly all of the surface-exposed region of the fibrillar M protein from Streptococcus pyogenes and is fused to the C-terminal attachment motif of the M molecule. The fusion protein is thus expressed on the surface of Streptococcus gordo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Infect Immun
Principais autores: Pozzi, G, Contorni, M, Oggioni, M R, Manganelli, R, Tommasino, M, Cavalieri, F, Fischetti, V A
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1992
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1563781/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.5.1902-1907.1992
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