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Involvement of Hat1p (Kat1p) Catalytic Activity and Subcellular Localization in Telomeric Silencing

Previous studies have shown that loss of the type B histone acetyltransferase Hat1p leads to defects in telomeric silencing in Saccharomyces cerevisiae. We used this phenotype to explore a number of functional characteristics of this enzyme. To determine whether the enzymatic activity of Hat1p is ne...

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Bibliographische Detailangaben
Hauptverfasser: Mersfelder, Erica L., Parthun, Mark R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570870/
https://ncbi.nlm.nih.gov/pubmed/18753131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802564200
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