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Ephrin-B2-induced Cleavage of EphB2 Receptor Is Mediated by Matrix Metalloproteinases to Trigger Cell Repulsion

EphB receptors provide crucial adhesive and repulsive signals during cell migration and axon guidance, but it is unclear how they switch between these opposing responses. Here we provide evidence of an important role for matrix metalloproteinases (MMPs) in repulsive EphB2 signaling. We found that Ep...

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書誌詳細
主要な著者: Lin, Kai-Ti, Sloniowski, Slawomir, Ethell, Douglas W., Ethell, Iryna M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570862/
https://ncbi.nlm.nih.gov/pubmed/18713744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804401200
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