Safety, immunogenicity, and efficacy of a Plasmodium falciparum vaccine comprising a circumsporozoite protein repeat region peptide conjugated to Pseudomonas aeruginosa toxin A.

Twenty-one malaria-naive volunteers were immunized with a vaccine consisting of a 22-kDa recombinant peptide (R32LR), derived from the repeat region of Plasmodium falciparum circumsporozoite (CS) protein, covalently coupled to detoxified Pseudomonas aeruginosa toxin A. Nineteen volunteers received a...

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Номзүйн дэлгэрэнгүй

-д хэвлэсэн:	Infect Immun
Үндсэн зохиолчид:	Fries, L F, Gordon, D M, Schneider, I, Beier, J C, Long, G W, Gross, M, Que, J U, Cryz, S J, Sadoff, J C
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology (ASM) 1992
Нөхцлүүд:	Research Article
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1563771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.5.1834-1839.1992
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