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Development of free-energy-based models for chaperonin containing TCP-1 mediated folding of actin

A free-energy-based approach is used to describe the mechanism through which chaperonin-containing TCP-1 (CCT) folds the filament-forming cytoskeletal protein actin, which is one of its primary substrates. The experimental observations on the actin folding and unfolding pathways are collated and the...

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Autors principals: Altschuler, Gabriel M, Willison, Keith R
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570749/
https://ncbi.nlm.nih.gov/pubmed/18708324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2008.0185
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