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Monoclonal antibody against Klebsiella capsular polysaccharide reduces severity and hematogenic spread of experimental Klebsiella pneumoniae pneumonia.

Klebsiella pneumoniae is an important nosocomial pathogen causing severe pulmonary infections. The majority of clinical Klebsiella isolates produce a high-molecular-weight capsular polysaccharide (CPS) which is one of the dominant virulence factors. In the present study, we examined the potency of a...

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Vydáno v:Infect Immun
Hlavní autoři: Held, T K, Trautmann, M, Mielke, M E, Neudeck, H, Cryz, S J, Cross, A S
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257072/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1563764/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.5.1771-1778.1992
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