Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells

BACKGROUND: Recent studies demonstrate that recombinant adeno-associated virus (rAAV)-based antigen loading of dendritic cells (DCs) generates in vitro, significant and rapid cytotoxic T-lymphocyte (CTL) responses against viral antigens. METHODS: We used the rAAV system to induce specific CTLs again...

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Autors principals: Yu, Yuefei, Pilgrim, Petra, Yan, Juqiang, Zhou, Wei, Jenkins, Marjorie, Gagliano, Nicoletta, Bumm, Klaus, Cannon, Martin, Milzani, Aldo, Dalle-Donne, Isabella, Kast, W Martin, Cobos, Everardo, Chiriva-Internati, Maurizio
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570669/
https://ncbi.nlm.nih.gov/pubmed/18834548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-6-56
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