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Histidine Residues at the Active Site of the Pasteurella multocida Toxin

We have investigated histidine residues near the active site of the mitogenic Pasteurella multocida toxin. Mutation of H1202 or H1228 had little effect, while the effect of mutation on H1223 depended on the amino acid substituted. Mutation of H1205 caused complete loss of activity, indicating its im...

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Detalhes bibliográficos
Main Authors: Pullinger, Gillian D, Lax, Alistair J
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570546/
https://ncbi.nlm.nih.gov/pubmed/18949067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874091X00701010007
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