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Histidine Residues at the Active Site of the Pasteurella multocida Toxin

We have investigated histidine residues near the active site of the mitogenic Pasteurella multocida toxin. Mutation of H1202 or H1228 had little effect, while the effect of mutation on H1223 depended on the amino acid substituted. Mutation of H1205 caused complete loss of activity, indicating its im...

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Détails bibliographiques
Auteurs principaux: Pullinger, Gillian D, Lax, Alistair J
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers Ltd. 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570546/
https://ncbi.nlm.nih.gov/pubmed/18949067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874091X00701010007
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