Platelet-induced clumping of Plasmodium falciparum-infected erythrocytes from Malawian patients with cerebral malaria - possible modulation in vivo by thrombocytopenia

Platelets may play a role in human cerebral malaria (CM) pathogenesis, and have been shown to induce the clumping of Plasmodium falciparum-parasitised red blood cells (PRBC) in vitro. Both thrombocytopenia and platelet-induced PRBC clumping are associated with severe malaria and especially with CM....

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Main Authors: WASSMER, Samuel Crocodile, TAYLOR, Terrie, MacLENNAN, Calman Alexander, KANJALA, Maxwell, MUKAKA, Mavuto, MOLYNEUX, Malcolm Edward, GRAU, Georges Emile
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570538/
https://ncbi.nlm.nih.gov/pubmed/18171288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/523761
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