PTCH mutations in basal cell carcinomas from azathioprine-treated organ transplant recipients

The immunosuppressant azathioprine is used to prevent graft rejection after organ transplantation. To investigate whether azathioprine-associated mutagenesis contributes to the high incidence of skin tumours in organ transplant recipients (OTRs), we analysed PTCH gene mutations in 60 basal cell carc...

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Detalhes bibliográficos
Main Authors: Harwood, C A, Attard, N R, O'Donovan, P, Chambers, P, Perrett, C M, Proby, C M, McGregor, J M, Karran, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570526/
https://ncbi.nlm.nih.gov/pubmed/18854826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604665
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