Deficiency of FLCN in Mouse Kidney Led to Development of Polycystic Kidneys and Renal Neoplasia

The Birt–Hogg–Dubé (BHD) disease is a genetic cancer syndrome. The responsible gene, BHD, has been identified by positional cloning and thought to be a novel tumor suppressor gene. BHD mutations cause many types of diseases including renal cell carcinomas, fibrofolliculomas, spontaneous pneumothorax...

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Detalhes bibliográficos
Main Authors: Chen, Jindong, Futami, Kunihiko, Petillo, David, Peng, Jun, Wang, Pengfei, Knol, Jared, Li, Yan, Khoo, Sok-Kean, Huang, Dan, Qian, Chao-Nan, Zhao, Ping, Dykyma, Karl, Zhang, Racheal, Cao, Brian, Yang, Ximing J., Furge, Kyle, Williams, Bart O., Teh, Bin Tean
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570491/
https://ncbi.nlm.nih.gov/pubmed/18974783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003581
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