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β-Cell Proliferation, but Not Neogenesis, Following 60% Partial Pancreatectomy Is Impaired in the Absence of FoxM1

OBJECTIVE—This study was designed to determine whether the transcription factor FoxM1 was required for regeneration of β-cell mass via proliferation and/or neogenesis in the adult after 60% partial pancreatectomy (PPx). RESEARCH DESIGN AND METHODS—Adult mice with a pancreas-wide deletion of Foxm1 (F...

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Detalles Bibliográficos
Main Authors: Ackermann Misfeldt, Amanda, Costa, Robert H., Gannon, Maureen
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570403/
https://ncbi.nlm.nih.gov/pubmed/18728229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0878
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