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Proteomic Analysis of the Balance between Survival and Cell Death Responses in Cisplatin-Mediated Ototoxicity
Cisplatin, a widely used anticancer drug, preferentially damages outer hair cells (OHCs) of the inner ear. In this study, an antibody microarray was used to identify early changes in protein expression in the rat cochlea induced by cisplatin. Only small changes in hearing thresholds (4−34 dB elevati...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570323/ https://ncbi.nlm.nih.gov/pubmed/18578524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr8002479 |
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