Inhibition of Nuclear Translocation of Apoptosis-Inducing Factor Is an Essential Mechanism of the Neuroprotective Activity of Pigment Epithelium-Derived Factor in a Rat Model of Retinal Degeneration

Photoreceptor apoptosis is a critical process of retinal degeneration in retinitis pigmentosa (RP), a group of retinal degenerative diseases that result from rod and cone photoreceptor cell death and represent a major cause of adult blindness. We previously demonstrated the efficient prevention of p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Murakami, Yusuke, Ikeda, Yasuhiro, Yonemitsu, Yoshikazu, Onimaru, Mitsuho, Nakagawa, Kazunori, Kohno, Ri-ichiro, Miyazaki, Masanori, Hisatomi, Toshio, Nakamura, Makoto, Yabe, Takeshi, Hasegawa, Mamoru, Ishibashi, Tatsuro, Sueishi, Katsuo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2008
Pynciau:
Regular Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570123/
https://ncbi.nlm.nih.gov/pubmed/18845835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080466
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