A Mutation in Rab38 Small GTPase Causes Abnormal Lung Surfactant Homeostasis and Aberrant Alveolar Structure in Mice

The chocolate mutation, which is associated with oculocutaneous albinism in mice, has been attributed to a G146T transversion in the conserved GTP/GDP-interacting domain of Rab38, a small GTPase that regulates intracellular vesicular trafficking. Rab38 displays a unique tissue-specific expression pa...

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Detalhes bibliográficos
Main Authors: Osanai, Kazuhiro, Oikawa, Rieko, Higuchi, Junko, Kobayashi, Makoto, Tsuchihara, Katsuma, Iguchi, Masaharu, Jongsu, Huang, Toga, Hirohisa, Voelker, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570118/
https://ncbi.nlm.nih.gov/pubmed/18832574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080056
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