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Alterations of DNA damage repair pathways resulting from JCV infection

Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disorder of the CNS caused by infection of glial cells with the polyomavirus, JCV. Here we report that genomic stability and DNA repair are significantly dysregulated by JCV infection of human astrocytes. Metaphase spreads exh...

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Detalhes bibliográficos
Main Authors: Darbinyan, Armine, White, Martyn K., Akan, Selma, Radhakrishnan, Sujatha, Valle, Luis Del, Amini, Shohreh, Khalili, Kamel
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570112/
https://ncbi.nlm.nih.gov/pubmed/17368705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.02.015
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