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Clinical efficacy of buprenorphine to minimize distress in MRL/lpr mice
MRL/MpJ-Fas(lpr) (MRL/lpr) mice are an accepted animal model to study human systemic lupus erythematosus. We tested if a commonly used analgesic (buprenorphine hydrochloride) would reduce pain and distress in these mice without impacting the progression of autoimmune disease. Female MRL/lpr mice wer...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570058/ https://ncbi.nlm.nih.gov/pubmed/17490635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2007.03.048 |
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