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Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon

BACKGROUND: The emergence and spread of Plasmodium falciparum resistance to almost all available antimalarial drugs necessitates the search for new chemotherapeutic compounds. The ubiquitin/proteasome system plays a major role in overall protein turnover, especially in fast dividing eukaryotic cells...

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Autors principals: Kreidenweiss, Andrea, Kremsner, Peter G, Mordmüller, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569964/
https://ncbi.nlm.nih.gov/pubmed/18816382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-187
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