Evaluation of human gene variant detection in amplicon pools by the GS-FLX parallel Pyrosequencer

BACKGROUND: A new priority in genome research is large-scale resequencing of genes to understand the molecular basis of hereditary disease and cancer. We assessed the ability of massively parallel pyrosequencing to identify sequence variants in pools. From a large collection of human PCR samples we...

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Hlavní autoři: Bordoni, Roberta, Bonnal, Raoul, Rizzi, Ermanno, Carrera, Paola, Benedetti, Sara, Cremonesi, Laura, Stenirri, Stefania, Colombo, Alessio, Montrasio, Cristina, Bonalumi, Sara, Albertini, Alberto, Bernardi, Luigi Rossi, Ferrari, Maurizio, De Bellis, Gianluca
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569949/
https://ncbi.nlm.nih.gov/pubmed/18842124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-464
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