Factors in Tissue Handling and Processing That Impact RNA Obtained From Formalin-fixed, Paraffin-embedded Tissue

Formalin-fixed, paraffin-embedded (FFPE) tissue is the most common specimen available for molecular assays on tissue after diagnostic histopathological examination. RNA from FFPE tissue suffers from strand breakage and cross-linking. Despite excellent extraction methods, RNA quality from FFPE materi...

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Autores principales: Chung, Joon-Yong, Braunschweig, Till, Williams, Reginald, Guerrero, Natalie, Hoffmann, Karl M., Kwon, Mijung, Song, Young K., Libutti, Steven K., Hewitt, Stephen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Histochemical Society 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569903/
https://ncbi.nlm.nih.gov/pubmed/18711211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2008.951863
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