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C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis

Caenorhabditis elegans SIR-2.1, a member of the sirtuin family related to Saccharomyces cerevisiae Sir2p, has previously been implicated in aging. The mammalian homolog SIRT1 plays important roles in multiple cellular processes including transcriptional repression and stress response. We show that s...

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Main Authors: Greiss, Sebastian, Hall, Julie, Ahmed, Shawn, Gartner, Anton
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569882/
https://ncbi.nlm.nih.gov/pubmed/18923081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.482608
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