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C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis

Caenorhabditis elegans SIR-2.1, a member of the sirtuin family related to Saccharomyces cerevisiae Sir2p, has previously been implicated in aging. The mammalian homolog SIRT1 plays important roles in multiple cellular processes including transcriptional repression and stress response. We show that s...

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Bibliografiset tiedot
Päätekijät: Greiss, Sebastian, Hall, Julie, Ahmed, Shawn, Gartner, Anton
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569882/
https://ncbi.nlm.nih.gov/pubmed/18923081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.482608
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