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Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases

BACKGROUND: Anthrax edema toxin (EdTx) is an adenylate cyclase which operates in the perinuclear region of host cells. However, the action of EdTx is poorly understood, especially at molecular level. The ability of EdTx to modulate cAMP-dependent signaling was studied in Jurkat T cells and was compa...

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Main Authors: Puhar, Andrea, Dal Molin, Federica, Horvath, Stéphanie, Ladants, Daniel, Montecucco, Cesare
格式: Artigo
語言:Inglês
出版: Public Library of Science 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569206/
https://ncbi.nlm.nih.gov/pubmed/18958164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003564
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