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Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases

BACKGROUND: Anthrax edema toxin (EdTx) is an adenylate cyclase which operates in the perinuclear region of host cells. However, the action of EdTx is poorly understood, especially at molecular level. The ability of EdTx to modulate cAMP-dependent signaling was studied in Jurkat T cells and was compa...

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Detalhes bibliográficos
Main Authors: Puhar, Andrea, Dal Molin, Federica, Horvath, Stéphanie, Ladants, Daniel, Montecucco, Cesare
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569206/
https://ncbi.nlm.nih.gov/pubmed/18958164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003564
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