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Recognition of Yeast mRNAs as “Nonsense Containing” Leads to Both Inhibition of mRNA Translation and mRNA Degradation: Implications for the Control of mRNA Decapping

A critical step in the degradation of many eukaryotic mRNAs is a decapping reaction that exposes the transcript to 5′ to 3′ exonucleolytic degradation. The dual role of the cap structure as a target of mRNA degradation and as the site of assembly of translation initiation factors has led to the hypo...

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Autori principali: Muhlrad, Denise, Parker, Roy
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25692/
https://ncbi.nlm.nih.gov/pubmed/10564284
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