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Two Distinct Signaling Pathways Downstream of Janus Kinase 2 Play Redundant Roles for Antiapoptotic Activity of Granulocyte-Macrophage Colony-stimulating Factor

Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) induces proliferation and sustains the viability of the mouse interleukin-3-dependent cell line BA/F3 expressing the hGM-CSF receptor. Analysis of the antiapoptosis activity of GM-CSF receptor βc mutants showed that box1 but not the C-...

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Autori principali: Liu, Rui, Itoh, Tohru, Arai, Ken-ichi, Watanabe, Sumiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25691/
https://ncbi.nlm.nih.gov/pubmed/10564283
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