Impairment of NO-Dependent Relaxation in Intralobar Pulmonary Arteries: Comparison of Urban Particulate Matter and Manufactured Nanoparticles

BACKGROUND AND OBJECTIVES: Because pulmonary circulation is the primary vascular target of inhaled particulate matter (PM), and nitric oxide is a major vasculoprotective agent, in this study we investigated the effect of various particles on the NO–cyclic guanosine monophosphate (cGMP) pathway in pu...

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Detalhes bibliográficos
Main Authors: Courtois, Arnaud, Andujar, Pascal, Ladeiro, Yannick, Baudrimont, Isabelle, Delannoy, Estelle, Leblais, Véronique, Begueret, Hugues, Galland, Marie Annick Billon, Brochard, Patrick, Marano, Francelyne, Marthan, Roger, Muller, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569085/
https://ncbi.nlm.nih.gov/pubmed/18941568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.11021
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