The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT

BACKGROUND: T-cell mediated immunity likely plays an important role in controlling HIV-1 infection and progression to AIDS. Several candidate vaccines against HIV-1 aim at stimulating cellular immune responses, either alone or together with the induction of neutralizing antibodies, and assays able t...

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Hlavní autoři: Kutscher, Sarah, Dembek, Claudia J, Allgayer, Simone, Heltai, Silvia, Stadlbauer, Birgit, Biswas, Priscilla, Nozza, Silvia, Tambussi, Giuseppe, Bogner, Johannes R, Stellbrink, Hans J, Goebel, Frank D, Lusso, Paolo, Tinelli, Marco, Poli, Guido, Erfle, Volker, Pohla, Heike, Malnati, Mauro, Cosma, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Methodology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569082/
https://ncbi.nlm.nih.gov/pubmed/18837993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-5-22
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