Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis

Despite high rates of exposure, only 5–10% of people infected with Mycobacterium tuberculosis will develop active tuberculosis (TB) disease, suggesting a significant role for genetic variation in the human immune response to this infection. Here, we studied TB association and expression of 18 genes...

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Bibliografische gegevens
Hoofdauteurs: Davila, Sonia, Hibberd, Martin L., Hari Dass, Ranjeeta, Wong, Hazel E. E., Sahiratmadja, Edhyana, Bonnard, Carine, Alisjahbana, Bachti, Szeszko, Jeffrey S., Balabanova, Yanina, Drobniewski, Francis, van Crevel, Reinout, van de Vosse, Esther, Nejentsev, Sergey, Ottenhoff, Tom H. M., Seielstad, Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2008
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568981/
https://ncbi.nlm.nih.gov/pubmed/18927625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000218
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