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Crystal Structure of Fosfomycin Resistance Kinase FomA from Streptomyces wedmorensis
The fosfomycin resistance protein FomA inactivates fosfomycin by phosphorylation of the phosphonate group of the antibiotic in the presence of ATP and Mg(II). We report the crystal structure of FomA from the fosfomycin biosynthetic gene cluster of Streptomyces wedmorensis in complex with diphosphate...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2568932/ https://ncbi.nlm.nih.gov/pubmed/18701452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803709200 |
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