Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine.

Mutants of herpes simplex virus type 1 resistant to the antiviral drug 9-beta-D-arabinofuranosyladenine (araA) have been isolated and characterized. AraA-resistant mutants can be isolated readily and appear at an appreciable frequency in low-passage stocks of wild-type virus. Of 13 newly isolated mu...

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izdano v:	J Virol
Principais autores:	Coen, D M, Furman, P A, Gelep, P T, Schaffer, P A
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1982
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6284981/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.41.3.909-918.1982
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