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Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowth, and axon targeting?
The highly polarized architecture of neurons is important for their function. Experimental data based on dominant-negative approaches suggest that the tumor suppressor adenomatous polyposis coli (APC), a regulator of Wnt signaling and the cytoskeleton, regulates polarity of neuroectodermal precursor...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2568018/ https://ncbi.nlm.nih.gov/pubmed/18852302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200807079 |
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