Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes

Activity-dependent secretion of brain-derived neurotrophic factor (BDNF) is thought to enhance synaptic plasticity, but the mechanisms controlling extracellular availability and clearance of secreted BDNF are poorly understood. We show that BDNF is secreted in its precursor form (pro-BDNF) and is th...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bergami, Matteo, Santi, Spartaco, Formaggio, Elena, Cagnoli, Cinzia, Verderio, Claudia, Blum, Robert, Berninger, Benedikt, Matteoli, Michela, Canossa, Marco
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2008
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568011/
https://ncbi.nlm.nih.gov/pubmed/18852301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806137
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