A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis

The dsRNA-binding protein Staufen was the first RNA-binding protein proven to play a role in RNA localization in Drosophila. A mammalian homolog, Staufen1 (Stau1), has been implicated in dendritic RNA localization in neurons, translational control, and mRNA decay. However, the precise mechanisms by...

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Главные авторы: Vessey, John P., Macchi, Paolo, Stein, Joel M., Mikl, Martin, Hawker, Kelvin N., Vogelsang, Petra, Wieczorek, Krzysztof, Vendra, Georgia, Riefler, Julia, Tübing, Fabian, Aparicio, Samuel A. J., Abel, Ted, Kiebler, Michael A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567905/
https://ncbi.nlm.nih.gov/pubmed/18922781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804583105
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