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Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice
BACKGROUND AND PURPOSE: Acute lung injury (ALI) remains a major challenge in critical care medicine. Both neutrophils and chemokines have been proposed as key components in the development of ALI. The main chemokine receptor on neutrophils is CXCR2, which regulates neutrophil recruitment and vascula...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567887/ https://ncbi.nlm.nih.gov/pubmed/18587419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.270 |
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