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Effects of pregabalin on visceral pain responses and colonic compliance in rats
BACKGROUND AND PURPOSE: Pregabalin, which binds to the α(2)-δ subunit of voltage-gated calcium channels, increased the threshold for pain during colorectal distension (CRD) in irritable bowel syndrome (IBS) patients. We tested the effects of oral pregabalin on the visceral pain-related viscerosomati...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567880/ https://ncbi.nlm.nih.gov/pubmed/18574457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.259 |
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