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Twenty-Four Hour Continuous Ghrelin Infusion Augments Physiologically Pulsatile, Nycthemeral, and Entropic (Feedback-Regulated) Modes of Growth Hormone Secretion

Background: Ghrelin is a 28-amino acid acylated peptide that potentiates GHRH stimulation and opposes somatostatin inhibition acutely. Whether prolonged ghrelin administration can sustain physiological patterns of GH secretion remains unknown. Hypothesis: Continuous delivery of ghrelin will amplify...

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Detalhes bibliográficos
Main Authors: Veldhuis, Johannes D., Reynolds, George Ann, Iranmanesh, Ali, Bowers, Cyril Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567861/
https://ncbi.nlm.nih.gov/pubmed/18593763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-0620
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