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Progestins in Hormone Replacement Therapies Reactivate Cancer Stem Cells in Women with Preexisting Breast Cancers: A Hypothesis
Why does hormone replacement therapy (HRT) with estrogens plus progestins increase the risk of breast cancer? First, experimental estrogen receptor-positive (ER(+)) and progesterone receptor-positive (PR(+)) human breast cancers contain a rare subpopulation of ER(−), PR(−) cancer stem cells. Especia...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Endocrine Society
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567860/ https://ncbi.nlm.nih.gov/pubmed/18647813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-0938 |
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