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Notch1 is an effector of Akt and hypoxia in melanoma development
Melanomas are highly aggressive neoplasms resistant to most conventional therapies. These tumors result from the interaction of altered intracellular tumor suppressors and oncogenes with the microenvironment in which these changes occur. We previously demonstrated that physiologic skin hypoxia contr...
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Main Authors: | , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
American Society for Clinical Investigation
2008
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567838/ https://ncbi.nlm.nih.gov/pubmed/18924608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36157 |
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