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Notch1 is an effector of Akt and hypoxia in melanoma development

Melanomas are highly aggressive neoplasms resistant to most conventional therapies. These tumors result from the interaction of altered intracellular tumor suppressors and oncogenes with the microenvironment in which these changes occur. We previously demonstrated that physiologic skin hypoxia contr...

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Sonraí Bibleagrafaíochta
Main Authors: Bedogni, Barbara, Warneke, James A., Nickoloff, Brian J., Giaccia, Amato J., Powell, Marianne Broome
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567838/
https://ncbi.nlm.nih.gov/pubmed/18924608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36157
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