Adenosine receptor antagonists alter the stability of human epileptic GABA(A) receptors

We examined how the endogenous anticonvulsant adenosine might influence γ-aminobutyric acid type A (GABA(A)) receptor stability and which adenosine receptors (ARs) were involved. Upon repetitive activation (GABA 500 μM), GABA(A) receptors, microtransplanted into Xenopus oocytes from neurosurgically...

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Main Authors: Roseti, Cristina, Martinello, Katiuscia, Fucile, Sergio, Piccari, Vanessa, Mascia, Addolorata, Di Gennaro, Giancarlo, Quarato, Pier Paolo, Manfredi, Mario, Esposito, Vincenzo, Cantore, Gianpaolo, Arcella, Antonella, Simonato, Michele, Fredholm, Bertil B., Limatola, Cristina, Miledi, Ricardo, Eusebi, Fabrizio
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567502/
https://ncbi.nlm.nih.gov/pubmed/18809912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807277105
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