A common variant in the 3′UTR of the GRIK4 glutamate receptor gene affects transcript abundance and protects against bipolar disorder

Underactivity of the glutamatergic system is an attractive model for the pathophysiology of several major mental illnesses. We previously described a chromosome abnormality disrupting the kainate class ionotropic glutamate receptor gene, GRIK4/KA1, in an individual with schizophrenia and learning di...

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Detalhes bibliográficos
Main Authors: Pickard, B. S., Knight, H. M., Hamilton, R. S., Soares, D. C., Walker, R., Boyd, J. K. F., Machell, J., Maclean, A., McGhee, K. A., Condie, A., Porteous, D. J., St. Clair, D., Davis, I., Blackwood, D. H. R., Muir, W. J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567472/
https://ncbi.nlm.nih.gov/pubmed/18824690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800643105
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